Culturomics: illuminating dark matter

Gregory Dubourg targetiing microbiota 2017Dr Grégory Dubourg from Aix-Marseille Université, France will talk about "Culturomics: illuminating dark matter" during the 5th Targeting Microbiota World Congress 2017.

According to Dr Grégory Dubourg "If over the last decade high-throughput sequencing techniques enabled substantial advance in the field of the human microbiome, several biases inherent to the methods led to consider other OMICS plateforms to exhaustively describe gut microbiota composition. Among these, the culturomics approach, based on large scale culture conditions and MALDI-TOF identification of isolates allowed to report to date the isolation of 280 new bacterial species. Of these, 125 were retrospectively detected as Operating Taxonomic Units  by metagenomics studies included in the Human Microbiome Project. In addition, culturomics approach allowed to double the number of prokaryotes cultured from the human gut. Filling a part of the metagenomics dark matter, culturomics also provides bioactive strains of potential interest for futher experiments."

For more information about Targeting Microbiota Congress, which will be held in Berlin on October 26-27, 2017:

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