What is the role of nasal microbiota in respiratory recurrent infections (RRI)?

Desiderio Passali Targeting microbiotaProf. Desiderio Passali, from University of Siena, Italy will present his studies on the “Role of nasal Microbiota in respiratory recurrent infections (RRI)” during the 5th Targeting Microbiota World Congress 2017.

According to Prof. Passali, the presence of a normal naso-sinusal microbial ecosystem, the so called nasal microbiota, is the mainstay for a good homeostasis of respiratory tract.

An imbalance of the nasal microbiota can lead to upper respiratory recurrent infections, which represent the most common illnesses in the patient outsetting.

Special interest grow up in the last years on possible approaches to restore the nasal microbiota. In this context, the topical administration of bacterial species belonging to the healthy human nasal microbiota can offers great benefits for the patient, contributing to the re-colonization process, re-establishing microbial balance, and reducing the level of potential pathogens and could represent a valid alternative to antibiotic.

In particular, the combination of two α-hemolytic streptococci, S. salivarius 24SMB and S. oralis 89a, was able to interfere, in vitro, with the biofilm formation capacity of pathogenic strains of the upper airway; moreover, this combination, resulted able, in various clinical trials, to significantly reduce the recurrence rates of upper respiratory infections.

For more information: www.targeting-microbiota.com

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